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RADIESSE® is a dermal filler made of smooth calcium hydroxylapatite (CaHA) microspheres. This formulation stimulates the body’s natural collagen production, resulting in a smoother, more youthful overall appearance. It is primarily used for adding volume to the cheeks and chin but is also FDA-approved for the treatment of the back of the hands. Because it is not hyaluronic acid-based, it is not reversible with Hylenex®. RADIESSE® typically lasts up to 15 months when used for contouring the face.